If the Najis fabric is from pork or dog or non Halal animal skin, then there is no way to clean or purify such material. If the Najis fabric is not Najis Al-A'yn, then you can wash it with water and make it Taahir.
Any material taken from Najis item is Najis as well. Fragrances derived from intoxicant alcohol is Najis. Applying such fragrances is permissible by itself, despite that fact that it is Najis, but you need to wash it before performing your Wudhu and/ or Prayers (Salah).
No, it is not 'necessary', and as for what is previously owned, that's also not necessary to ascertain, or to wash. If you want to wash the animal, you can, but it's not wajib.
Istihadha requires you to perform Wudhu for every single Salah whether obligatory or recommended. If the Istihadha has occurred before performing your Salah, your every Salah needs to be with a new Wudhu.
If Istihadha occurred immediately after you performed your Prayers,v your Prayers which performed are valid, but coming prayers need a new Wudhu for every Prayer. This is when the blood is little which does not fill the pad.
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